Lhasa Limited shared knowledge shared progress

Interrogating AOP-Wiki knowledge as a network

pdf fileKane S;

Adverse outcome pathways (AOPs) represent a formalised knowledge framework for capturing mechanisms leading to toxicity. 

AOPs are a key tool in the development of integrated approaches to testing and assessment (IATA) and AOP-Wiki is the main public repository of this knowledge.

The data available from this resource can be viewed as single linear AOPs and, while this representation is valuable, new emergent pathways and previously unknown relationships can be discovered if the AOPs are viewed as a network. 

Kaptis is an application developed by Lhasa which allows users to store, search and edit AOP knowledge. A key feature is the functionality to visualise AOPs as AOP networks from a selected Key Event (KE).


Additional Documents

    © 2022 Lhasa Limited | Registered office: Granary Wharf House, 2 Canal Wharf, Leeds, LS11 5PS, UK Tel: +44 (0)113 394 6020
    VAT number 396 8737 77 | Lhasa Limited is registered as a charity (290866)| Company Registration Number 01765239 (England and Wales).

    Apart from the free survey software, we also have access to QuestionPro's free survey templates . We've found many of them useful and powerful to collect insights from various stakeholders of our organization.