Metabolite identification and analysis
Determining metabolic fate of chemicals within drug development
Identification and analysis of metabolic fate of a chemical substance and the associated potential toxicity of the parent compound, or its metabolites, is a critical aspect of drug development.
Metabolic understanding in early drug research can save time in drug development and enhance the late-stage drug survival rate.
Computational approaches for the prediction of metabolic fate have been developed to support early screening for metabolites and greater transparency and control over metabolic fate.
Meteor Nexus highlights
In-depth knowledge of metabolic transformations and filtering options within Meteor Nexus helps with structure elucidation of experimentally observed metabolites.
Analyse metabolite predictions
Meteor Nexus metabolic fate predictions are clearly presented and contain detailed supporting evidence associated with the biotransformations predicted.
Access metabolism knowledge
We continuously improve and add to the knowledge within Meteor Nexus, utilising both public and proprietary data, resulting in vast coverage of biotransformations.
Have you read our collaborative paper, published with the National Institute of Health Sciences (NIHS) of Japan? The paper is based on …
We are delighted to announce that our paper ‘Using adverse outcome pathways to contextualise (Q)SAR predictions for reproductive toxicity – A case …