We had a fantastic time at this year’s Society of Toxicology (SOT) in Nashville, Tennessee, where Principal Scientist, Dr. Martyn Chilton was shortlisted for two Best Overall Abstract awards! Martyn was awarded ‘Top 10 Best Computational Toxicology Specialty Section (CTSS) Abstract’ and ‘Top 10 Best Risk Assessment Speciality Section (RASS) Abstract’ for his poster which …
Hello! My name is Gabriela Silveria, and I work in the Applied Sciences team as a Senior Application Scientist at Lhasa Limited. In my role I work as a bridge between members and Lhasa scientists. I educate members on how to make best use of our software, and capture their feedback to improve our solutions …
In November last year, we published a ground-breaking article to Chemical Research in Toxicology titled ‘What Makes a Potent Nitrosamine? Statistical Validation of Expert-Derived Structure–Activity Relationships’. Within the paper, we show that certain structural features, when treated independently, have a statistically significant impact on the carcinogenic potency of nitrosamines. It is with great excitement that …
One of the most influential scientific papers of 2022 Read More »
Welcome to 2023, I hope you are feeling enthusiastic about the year ahead. I am not one for New Year’s resolutions, however, I do have a sense of excitement about the opportunities that a New Year brings. For us at Lhasa, 2023 marks the end of our BHAG period. If you are wondering, “What on earth is …
Hola! My name is Jessica Magallanes-Castaneda. I am originally from Mexico and moved to the UK in 2015 to pursue my MSc and PhD in Computer Science at The University of Sheffield. I am very happy to have joined Lhasa in May 2022, keep reading on to find out why! I work within the Software …
A day in the life of a Software Developer at Lhasa Limited Read More »
Mutagenic impurities can be expected in any drug product; however, this is not a concern providing they are present below the safe limit. The objective of a carcinogenicity study is to identify compounds that can cause tumours in animals, which is imperative to understanding the cancer risk posed to humans. ICH M7 in practice The …
How to calculate the safe limit for carcinogens as per ICH M7 Read More »
We are absolutely thrilled to have won the Tech4Good (Product) award at the 2022 Leeds Digital Festival! We were delighted to be shortlisted, alongside some amazing organisations, and it is a real honour to win the award. The Leeds Digital Festival is an annual tech event in Leeds which is a celebration of digital culture in …
Data sharing initiatives allow researchers and scientists to share data and knowledge in order to improve and accelerate scientific progress and discovery. These initiatives are therefore at the heart of our Lhasa Limited ethos “Shared knowledge, shared progress“. In response to the nitrosamine crisis, we partnered with the pharmaceutical industry to launch a data sharing …
The benefits of joining the Complex Nitrosamines consortium Read More »
Evaluating the potential toxicity of chemicals is an important part of the drug development process. Optimizing a data set that provides quality over quantity is critical in the search for suitable drug candidates. Developed by our scientists, Vitic is a chemical database and information management system that provides rapid access to high-quality toxicity data from …
Ensuring data quality in Vitic; three benchmarks for data quality success Read More »
I recently read that by 2025, 36% of world data will be healthcare data. (Yes, thirty-six percent!). Considering this statistic, now more than ever, it is important that we are working to ensure existing data is utilised to make better safety assessment decisions more quickly – whilst also relying less on animal testing. Within many sectors …
Using existing data better and relying less on animal testing Read More »
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