Events
When
26 October 2020
2020 Lhasa Limited Virtual Symposium: The Application of Adverse Outcome Pathways (AOPs) for Risk Assessment
Virtual Conference

Lhasa Limited was pleased to host a virtual symposium made up of a series of 4 webinars.
The theme of Lhasa's 2020 virtual symposium was the application of adverse outcome pathways (AOPs).
Each webinar session associated with this event featured presentations from both a Lhasa Limited scientist and an industry based guest speaker.
Please see speaker and presentation details for each session below, followed by recordings and slides:
Session 1 - 5th October 2020 - The application of adverse outcome pathways (AOPs) to improve risk assessments for development and reproductive toxicity (DART)
- Guest speaker: Richard Currie, Principal Technical Expert at Syngenta
- Guest speaker presentation title: Building quantitative AOPs of the DARTable genome to explore risks of developmental toxicity.
- Lhasa speaker: Adrian Fowkes, Science Team Leader
- Lhasa speaker presentation title: Creating a DART AOP network to enable improved decision-making during risk assessments.
Session 2 - 12th October 2020 - Application of adverse outcome pathways (AOPs) to support integrated approaches to testing and assessment (IATA)
- Guest speaker: Jason O'Brien, Health Canada
- Guest speaker presentation title: AOP and IATA Complimentary Frameworks to Modernize Chemical Risk Assessment.
- Lhasa speaker: Steve Kane, Scientist
- Lhasa speaker presentation title: Integration of adverse outcome pathways (AOP) with experimental data to support the assessment of carcinogenic risk.
Session 3 - 19th October 2020 - The potential utility of AOPs in the future of regulatory decision-making
- Guest speaker: David Jones, Expert Pharmaco Toxicologist at MHRA
- Guest speaker presentation title: A pharmaceutical assessor’s view on the utility of adverse outcome pathways.
- Lhasa speaker: Susanne Stalford, Senior Scientist
- Lhasa speaker presentation title: Exploiting AOPs as a framework to support ICH S1 risk assessments
Session 4 - 26th October 2020 - Harnessing the potential of adverse outcome pathways in the assessment of genotoxicity
- Guest speaker: Carole Yauk, Lead of the Genomics Laboratory at Health Canada
- Guest speaker presentation title: Collaborative efforts leading to a growing genetic toxicology AOP network.
- Lhasa speaker: Alex Cayley, Senior Scientist
- Lhasa speaker presentation title: Combining knowledge and data on an AOP framework in order to take advantage of new and emerging methods in genotoxicity assessment.
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Related Publications
- Session 1 - Building quantitative AOPs of the DARTable genome to explore risks of developmental toxicity - Recording
- Session 1 - Building quantitative AOPs of the DARTable genome to explore risks of developmental toxicity - Slides
- Session 1 - Creating a DART AOP network to enable improved decision-making during risk assessments - Recording
- Session 1 - Creating a DART AOP network to enable improved decision-making during risk assessments - Slides
- Session 2 - AOP and IATA complimentary frameworks to modernize chemical risk assessment - Recording
- Session 2 - AOP and IATA complimentary frameworks to modernize chemical risk assessment - Slides
- Session 2 - Integration of adverse outcome pathways with experimental data to support the assessment of carcinogenic risk - Recording
- Session 2 - Integration of adverse outcome pathways with experimental data to support the assessment of carcinogenic risk - Slides
- Session 3 - A pharmaceutical regulator’s view on the utility of adverse outcome pathways for carcinogenicity assessment - Recording
- Session 3 - A pharmaceutical regulator’s view on the utility of adverse outcome pathways for carcinogenicity assessment - Slides
- Session 3 - Exploiting AOPs as a framework to support ICH S1 risk assessments - Recording
- Session 3 - Exploiting AOPs as a framework to support ICH S1 risk assessments - Slides
- Session 4 - Combining knowledge and data on an AOP framework in order to take advantage of new and emerging methods In genotoxicity assessment - Recording
- Session 4 - Combining knowledge and data on an AOP framework in order to take advantage of new and emerging methods In genotoxicity assessment - Slides
- Session 4 - The growing network of genotoxicity AOPs - Recording
- Session 4 - The growing network of genotoxicityAOPs - Slides