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    AUG 2022
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Validation of Nexus v.2.5.2 for Ames Mutagenicity

pdf fileFoster RS;

The following statistics have been generated using the mutagenicity in vitro endpoint in Derek KB 2022.2 in Derek Nexus v.6.2.1, Sarah Model – 2022.2 in Sarah Nexus v.3.2.1 and ICH M7 Prediction in Nexus v.2.5.2. Validations for each program have been conducted against a selection of datasets containing proprietary Ames data. Performance statistics are provided for the predictions against all datasets combined.


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