Lhasa scientist Jade Jones presented her award-winning poster at the European Teratology Society Conference.
Challenging the general requirement for two mammalian species in Developmental and Reproductive Toxicity (DART) studies, this work highlights that rats and rabbits are typically equally sensitive, and true species-specific differences are rare. By utilising an Adverse Outcome Pathway (AOP) framework integrated with species sensitivity knowledge, this approach provides the scientific rationale needed to support confident regulatory decisions regarding the sufficiency of single-species DART assessments.