Chemical
Related Publications
- A Defined Approach for Predicting Skin Sensitisation Hazard and Potency
- A Defined Approach to Skin Sensitization Using Derek Nexus and Non-Animal Assays
- A Nitrite Excipient Database: A Useful Tool to Support N-Nitrosamine Risk Assessments for Drug Products
- A pharma-wide approach to address the genotoxicity prediction of primary aromatic amines.
- A practical application of two in silico systems for identification of potentially mutagenic impurities
- A quantitative in silico model for predicting skin sensitization using a nearest neighbours approach within expert-derived structure–activity alert spaces
- Addressing the Challenge of Making Negative Predictions for Skin Sensitisation
- Addressing the Challenge of Making Negative Predictions for Skin Sensitisation - A Summary
- Addressing toxicity risk when designing and selecting compounds in early drug discovery
- An Elemental Impurities Excipient Database: A Viable Tool for ICH Q3D Drug Product Risk Assessment
- An evaluation of in-house and off-the-shelf in silico models: Implications on guidance for mutagenicity assessment
- An Expert System To Predict the Forced Degradation of Organic Molecules
- An in Silico Method for Predicting Ames Activities of Primary Aromatic Amines
- An Overview of Lhasa Limited Collaborative Data Sharing Initiatives
- Assessing confidence in predictions made by knowledge-based systems
- Assessing Confidence in Predictions.wmv
- Benchmarking Assessment of Salmonella Mutagenicity QSAR Models for Potential Use Under ICH M7.pdf
- Biotransformation Pathways of Biocides and Pharmaceuticals in Freshwater Crustaceans
- Bringing Together Scientific Disciplines for Collaborative Undertakings: A Vision for Advancing the Adverse Outcome Pathway Framework
- Capturing and curating in vitro data from diverse sources to support MIE investigation for hepatotoxicity
- Current advances in skin sensitization in silico predictions and their use in a defined approach
- Derek Nexus and the Prediction of Human Skin Sensitisation Potential: An Evaluation
- Derek Nexus Carcinogenicity QMRF.pdf
- Derek Nexus Chromosome Damage QMRF.pdf
- Derek Nexus HERG QMRF.pdf
- Derek Nexus Mutagenicity QMRF.pdf
- Derek Nexus Skin Sensitisation QMRF.pdf
- Derek Nexus Teratogenicity QMRF.pdf
- Developing structure-activity relationships for N-nitrosamine activity
- Developing Structure-Activity Relationships for the Prediction of Hepatotoxicity
- Enhancing the ICH M7 Workflow through Setaria
- Evaluation Of A Statistics-based Ames Mutagenicity QSAR Model And Interpretation Of The Results Obtained
- Expert Review of In Silico Predictions for Skin Sensitization Potency
- Expert Systems - The Use of Expert Systems in Drug Design-Toxicity and Metabolism
- Food for thought - A toxicology ontology roadmap
- How To - Filtering Mass Defect
- ICH M7 Classification Workflow
- Improvements to in silico predictivity after access to proprietary data
- In Silico Prediction of DILI - Extraction of Histopathology Data from Preclinical Toxicity Data Studies of the eTOX Database for new In SIlico Models of Hepatotoxicity
- In Silico Prediction of Genotoxicity Current Applications and Future Perspectives
- It’s difficult, but important, to make negative predictions
- Machine Learning Predicts Degree of Aromaticity from Structural Fingerprints
- Making reliable negative predictions of human skin sensitisation using an in silico fragmentation approach
- Mutagenic impurities: predicting alerting structures using in silico tools
- Mutagenicity assessment strategy for pharmaceutical intermediates to aid limit setting for occupational exposure
- Negative Predictions for Skin Sensitisation
- Nexus 2.2: An Overview of Key New Features - Derek and Meteor Nexus
- Nexus 2.2: An Overview of Key New Features - Sarah Nexus
- Nothing to report? An in silico fragmentation methodology for making explicit negative predictions of skin sensitisation
- Performance of Derek Nexus’ In Silico EC3 Model for Predicting Dermal Sensitization Potency
- Practical Implementation of (Q)SAR and Expert Review for Compliance with ICH M7 Guidelines
- Predicting skin sensitisation using a decision tree integrated testing strategy with an in silico model and in chemico/in vitro assays
- Predicting the Purging of Impurities within an API Synthetic Pathway
- Sarah Nexus Strain Information
- Sarah Nexus: The Statistical System for ICH M7
- Skin sensitisation - What place does in silico have within a defined approach?
- Strain profiles: Moving beyond binary Ames classification
- Strain Profiles: Moving Beyond Binary Ames Classification - A Summary
- Summation of Toxicity Data in Vitic
- The Liability Load and how Lhasa Limited Focuses on Reducing it
- Undertaking Expert Review under ICH M7 - A Practical Guide
- Utilization Of Derek Nexus Dermal Sensitization Predictions For Hazard Assessment At Bristol-Myers Squibb
- Vitic - A Faster, More Efficient Searching Experience
- Who is using Vitic? Infographic
- Workbook: Expert Review of EC3 Predictions - a workshop
- Zeneth Member Type Infographic
- Zeneth: an in silico tool to aid identification of degradants