Cosmetic
Related Publications
- A defined approach for predicting skin sensitisation hazard and potency based on the guided integration of in silico, in chemico and in vitro data using exclusion criteria
- A practical application of two in silico systems for identification of potentially mutagenic impurities
- A quantitative in silico model for predicting skin sensitization using a nearest neighbours approach within expert-derived structure–activity alert spaces
- Addressing toxicity risk when designing and selecting compounds in early drug discovery
- An evaluation of in-house and off-the-shelf in silico models: Implications on guidance for mutagenicity assessment
- An Expert System To Predict the Forced Degradation of Organic Molecules
- An in Silico Method for Predicting Ames Activities of Primary Aromatic Amines
- An Overview of Recent Skin Sensitisation Work at Lhasa
- Assessing confidence in predictions made by knowledge-based systems
- Assessing Confidence in Predictions.wmv
- Biotransformation Pathways of Biocides and Pharmaceuticals in Freshwater Crustaceans
- Case study on the use of integrated approaches to testing and assessment for the prediction of a 90-day repeated dose toxicity study (OECD 408) for 2-Ethylbutyric acid using a read-across approach from other branched carboxylic acids.
- Derek Nexus - Achieving High Accuracy with High Coverage
- Developing Structure-Activity Relationships for the Prediction of Hepatotoxicity
- EC3: Methodology Explained
- Evaluation of the Global Performance of Eight In Silico Skin Sensitization Models Using Human Data
- Expert Review of EC3 Predictions
- Expert Systems - The Use of Expert Systems in Drug Design-Toxicity and Metabolism
- Food for thought - A toxicology ontology roadmap
- How to resolve inconclusive predictions from defined approaches for skin sensitisation in OECD Guideline No. 497
- How Well Do Defined Approaches Predict the Human Skin Sensitisation Potential of Previously Untested Chemicals?
- HuskinDB, a database for skin permeation of xenobiotics
- It’s difficult, but important, to make negative predictions
- Lhasa Limited's Skin Sensitisation Assessment Portfolio Infographic
- Mutagenicity assessment strategy for pharmaceutical intermediates to aid limit setting for occupational exposure
- Negative Predictions for Skin Sensitisation
- Nexus 2.2: An Overview of Key New Features - Sarah Nexus
- Phosphite esters: a novel class of contact allergen
- Practical Implementation of (Q)SAR and Expert Review for Compliance with ICH M7 Guidelines
- Predicting the Purging of Impurities within an API Synthetic Pathway
- Prediction of genotoxic potential of cosmetic ingredients by an in silico battery system consisting of a combination of an expert rule-based system and a statistics-based system
- Summation of Toxicity Data in Vitic
- The interchangeability of in vitro key event-based skin sensitisation assays - impact on defined approaches
- The Liability Load and how Lhasa Limited Focuses on Reducing it
- Updated Dermal Sensitisation Thresholds derived using an in silico expert system and an expanded Local Lymph Node Assay dataset
- Using Derek Nexus as part of a skin sensitisation integrated testing strategy (ITS)
- Using Derek Nexus to assess the safety of raw materials used in cosmetics
- Vitic Data Sharing Benefits
- Webinar - A defined approach for predicting skin sensitisation hazard and potency.
- Who is using Vitic? Infographic
- Workbook: Expert Review of EC3 Predictions - a workshop