Applicability Domain: Towards a more formal definition
These slides were presented by Thierry Hanser at QSAR 2016.
The presentation aims:
- Applicability Domain (AD) is not a monolithic concept: there are 3 key layers
- Separation of concerns can help clarify and formalise the notion of AD
- Purpose: Initiate a constructive discussion among the (Q)SAR community to build a common understanding together
- Harmonize the way we define and present AD to the end user across models and applications
- Remove confusion for the end user and improve the value of AD model