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- Publisher:Chemical Research in Toxicology
- Publication Date:May 2022
- Publication Type:Paper
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An Evaluation of the Occupational Health Hazards of Peptide Couplers
This scientific paper evaluates the occupational health hazards of 25 commonly used peptide couplers and a select group of their hydrolysis products for in vivo, in vitro, and in silico testing.
The study demonstrates the merits of an integrated, in vivo -in silico analysis, applied to the skin sensitisation endpoint using Computer-Aided Discovery and REdesign (CADRE) and Derek Nexus.
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