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  • Publisher:
  • Publication Date:
    Jun 2008
  • Reference:
    Dalton Transactions, 2008, 14(22), pp2920-2922
  • DOI:
    10.1039/b805110k
  • PMID:
    18493625
  • Publication Type:
    Paper
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A technetium intermediate specifically promotes deprotection of trifluoroacetyl HYNIC during radiolabelling under mild conditions

Biagini S; Blower PJ; Surfraz B;

The trifluoroacetyl group protects the nucleophilic HYNIC from unwanted side reactions yet allows radiolabelling with technetium-99m under mild conditions, due to efficient and specific promotion of deprotection by a technetium complex intermediate.

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