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Publications
  • Publisher:
    Society of Nuclear Medicine
  • Publication Date:
    Mar 2009
  • Reference:
    Journal of Nuclear Medicine, 2009, 50(4), pp591-598
  • DOI:
    10.2967/jnumed.108.058289
  • PMID:
    19289435
  • Publication Type:
    Paper
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99mTc-HYNIC-Gastrin Peptides: Assisted Coordination of 99mTc by Amino Acid Side Chains Results in Improved Performance Both In Vitro and In Vivo

Biagini S; Blower PJ; Finucane C; King R; Mather SJ; Surfraz B;

The aim of this study was to determine the effects of assisted coordination by amino acids such as histidine and glutamic acid on the function of (99m)Tc-labeled gastrin peptide-hydrazinonicotinamide (HYNIC) conjugates and their ability to target cholecystokinin-R in small-animal models.

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