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Derek NexusDerek Nexus is the expert, knowledge-based software that gives you accurate toxicity predictions quickly. Early, accurate in silico toxicity tests using Derek Nexus is the quick, inexpensive way to identify potentially toxic chemicals, aiding your experts in rejecting unsuitable drug candidates.MirabilisMirabilis is an industry-standardised approach providing an expert and scientifically robust software for the calculation of purge factors of potentially mutagenic impurities in a synthetic route.Sarah NexusSarah Nexus is a statistical software tool that gives you accurate mutagenicity predictions quickly.ViticVitic is the next generation chemical database and information management system, offering researchers and scientists rapid access to searchable toxicological information. Early review of Vitic is the quick, inexpensive way to identify potentially toxic chemicals, and therefore reject unsuitable drug candidates.
Vitic Nexus is your trusted toxicity expert and management system; containing data implemented by scientists at Lhasa Limited, who continually work on the toxicity database with current toxicological knowledge.ZenethZeneth is an expert, knowledge-based software that gives you accurate forced degradation predictions quickly. Zeneth is the perfect cost-effective solution for scientists who need to understand the forced degradation pathways of organic compounds.
Zeneth is your trusted degradation expert system. It is based on data implemented by scientists at Lhasa Limited, who continually work on the transformation knowledge base with current transformation knowledge.
Related sites
ICH M7 final guidelines R1 (31 March 2017)ICH guideline on "Assessment and Control of DNA Reactive (Mutagenic) Impurities in Pharmaceuticals to Limit Potential Carcinogenic Risk"ICH Multidisciplinary guidelinesAccess the most current version of any of the ICH M# guidelines
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Skin Sensitisation
Lhasa Limited has a focus on skin sensitisation, an important endpoint for many industries:
- Derek Nexus contains expert-derived functionality for assessment of the skin sensitisation endpoint. Derek provides quantitative EC3 predictions for skin sensitisation as well as negative predictions for those query compounds which do not fire a skin sensitisation alert.
- Lhasa has created a free, online application implementing its Defined Approach for skin sensitisation.
