Lhasa Limited introduces Vitic (version 2025.1.0), an expertly curated toxicity database with a variety of new data releases to further support insights into carcinogenicity and strengthen existing endpoints.
Unlocking the latest version of Vitic
The latest release encompasses 10,814 total new data records and 139 new substances.
Added to support chemical safety decision-making in pharmaceutical and life science research and development, the latest records will reinforce reliability in chemical safety assessments through expert data.
Expansions of the complete toxicity database are populated and peer-reviewed by scientists at Lhasa Limited to ensure quality and confidence. Lhasa is driven by collaboration across industry and regulatory landscapes, with Vitic encapsulating this mission through significant public, proprietary, and regulatory shared data.
Peer-assessed and expertly reviewed, new Vitic datasets support members to make reliable toxicological decisions with data at the centre.
Here are some key areas across the latest updates which offer innovative support for chemical risk assessments:
- Rich carcinogenicity data to enhance risk assessments and allow for confident decision-making using advanced carcinogenic potency and safety limits.
- Well-developed endpoints to strengthen quick and efficient structure searching for chemical safety assessments, whilst mitigating analytical testing needs.
- Broadened Vitic toxicity records to expand the scope of potential reliable conclusions and scientific justifications that can be made to safeguard human health.
To access the latest records, in-house installations will require a software recipient to download the release file from the Lhasa Download Centre. Online and cloud-based members will see the latest release readily available upon their next login.
Additional benefits to members
The latest updates in carcinogenicity data also facilitates toxicity predictions.
Vitic empowers close-match structure identification, and the expansive and continuously evolving dataset helps fill data gaps through collaboration with Acrostic, a powerful read-across solution.
Join the data sharing initiative
As a wider vision, Lhasa aims to support regulatory submissions without the need for animal testing. Through unique data sharing initiatives, Lhasa continues to minimise the quantity of preclinical in vivo toxicity studies and reduce the overarching requirements for in-house experimental or analytical testing data.
Pre-competitive data sharing facilitates the filling of critical industry data gaps whilst also empowering the replacement of in vivo with in silico solutions, like Vitic. High-quality toxicity data is instrumental in improving the understanding of Structure Activity Relationships (SARs) used to refine Derek Nexus, a leading expert knowledge-based software and computational tool deployed in predictive toxicology.
Joining an anonymous data sharing initiative helps build the foundation of high-quality, data-led decisions, which will meet regulatory expectations around chemical safety and toxicity.
Lhasa Limited supports members in maximising the value of their toxicity data. For training or queries relating to the latest Vitic release, contact the Applied Sciences Team.
Those interested in uncovering the power of data-led decision making can book a Vitic demonstration here.
Solution benefits are accessible to members through separate licensing of Lhasa Limited solutions. For those interested in Acrostic or Derek Nexus, get in touch here.