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Developments continue within the Lhasa Intermediates data sharing initiative enhancing risk assessments

Lhasa Limited is delighted to announce the release of new data to the Vitic Intermediates database.


This pre-competitive data sharing initiative facilitates anonymous sharing of Ames mutagenicity results, for common intermediates and compounds containing functional groups of interest. Access to this additional data supports more accurate risk assessments.

New data release

With the latest update, the Vitic Intermediates 2024.1.0 database now contains:

  • 2,011 new data records, bringing the total to 39,752,
  • 105 new substances, bringing the total to 2,152.

An update to note is the addition of 1,906 genetic toxicity in vitro data records within the database – bringing the total number of data records to 37,603. The new data records relate to 110 substances, of which 105 are new substances.

Among the new compounds, coverage continues to improve for classes highly relevant to drug synthesis, such as alkylating agents, aromatic nitro compounds, and arylboronic acids.

How does the Vitic Intermediates data sharing initiative work?

Consortium members securely contribute data from their internal portfolio or generate new data as part of the directed testing of commercially available compounds. The objective thereby is to match substructures prioritised by Lhasa scientists and members to improve structure-activity relationship (SAR) mutagenicity predictions. The data is shared in an anonymised and standardised format within the database, contributing to reduced testing efforts by preventing duplication.

Interested in joining the consortium? Get in touch with the Lhasa team.