Lhasa Limited shared knowledge shared progress

Publications

The following links provide access to relevant publications for the last 2 years. If you would like to view older publications, or to refine your search criteria further please search the library.

TitlePublishedTypeProducts
In Silico Prediction of Genotoxicity Current Applications and Future PerspectivesSeptember 2021pdf fileDerek NexusSarah Nexus
Machine Learning Predicts Degree of Aromaticity from Structural FingerprintsNovember 2020
Session 4 - The growing network of genotoxicity AOPs - RecordingOctober 2020
Session 4 - The growing network of genotoxicityAOPs - SlidesOctober 2020pdf file
Use of Mirabilis based purge calculations to understand Nitrosamine-related risk and control strategy optionsJuly 2020Mirabilis
Vitic Data Sharing BenefitsApril 2020pdf fileVitic Nexus
Setting the basis for the mutagenicity assessment of new dyes: Application to the Max Weaver Dye LibraryAugust 2019pdf fileDerek Nexus
Improving In Silico Predictions in Developmental and Reproductive ToxicologyApril 2019Derek NexusSarah Nexus
Enhancing the ICH M7 Workflow through SetariaDecember 2018pdf fileSetaria
Important considerations for the validation of QSAR models for in vitro mutagenicityNovember 2018Derek NexusSarah NexusVitic Nexus
Zeneth: an in silico tool to aid identification of degradantsOctober 2018pdf fileZeneth
Developing an adverse outcome pathway framework for carcinogenicity from alerts in an expert rule-based systemSeptember 2018pdf fileDerek Nexus
Sarah Nexus Strain InformationMarch 2018pdf fileSarah Nexus
Strain profiles: Moving beyond binary Ames classificationMarch 2018pdf fileSarah Nexus
Addressing the Challenge of Making Negative Predictions for Skin SensitisationMarch 2018pdf fileDerek Nexus
Derek Nexus and the Prediction of Human Skin Sensitisation Potential: An EvaluationMarch 2018pdf fileDerek Nexus
Nexus 2.2: An Overview of Key New Features - Derek and Meteor NexusJanuary 2018Derek NexusMeteor Nexus
Sarah Nexus: The Statistical System for ICH M7November 2017pdf fileSarah Nexus
An Overview of Lhasa Limited Collaborative Data Sharing InitiativesOctober 2017pdf fileDerek NexusETOXExcipientsIntermediatesVitic NexusiPiEMeteor NexusMIP DILIMirabilisSarah NexusSetariaZeneth
Workbook: Expert Review of EC3 Predictions - a workshopMarch 2017pdf fileDerek Nexus
The Liability Load and how Lhasa Limited Focuses on Reducing itNovember 2016pdf fileDerek NexusSarah Nexus
Practical Implementation of (Q)SAR and Expert Review for Compliance with ICH M7 GuidelinesApril 2016pdf file
Predicting the Purging of Impurities within an API Synthetic PathwayApril 2016pdf file
Improvements to in silico predictivity after access to proprietary dataApril 2016Derek Nexus
Summation of Toxicity Data in ViticMarch 2016Vitic Nexus
Predicting skin sensitisation using a decision tree integrated testing strategy with an in silico model and in chemico/in vitro assaysJanuary 2016Derek Nexus
It’s difficult, but important, to make negative predictionsJanuary 2016Derek Nexus
Evaluation Of A Statistics-based Ames Mutagenicity QSAR Model And Interpretation Of The Results ObtainedDecember 2015Sarah Nexus
Mutagenicity assessment strategy for pharmaceutical intermediates to aid limit setting for occupational exposureNovember 2015Sarah NexusDerek Nexus
A practical application of two in silico systems for identification of potentially mutagenic impuritiesMay 2015Derek NexusSarah Nexus
An evaluation of in-house and off-the-shelf in silico models: Implications on guidance for mutagenicity assessmentApril 2015Derek Nexus
How To - Filtering Mass DefectDecember 2014Meteor Nexus
Introduction to in silico toxicologyOctober 2014Derek NexusSarah Nexus
Benchmarking Assessment of Salmonella Mutagenicity QSAR Models for Potential Use Under ICH M7.pdfMarch 2014pdf fileSarah Nexus
An Expert System To Predict the Forced Degradation of Organic MoleculesJuly 2013Zeneth
Assessing Confidence in Predictions.wmvMay 2013Derek Nexus
Biotransformation Pathways of Biocides and Pharmaceuticals in Freshwater CrustaceansFebruary 2013Meteor Nexus
Food for thought - A toxicology ontology roadmapDecember 2012Derek Nexus
Assessing confidence in predictions made by knowledge-based systemsSeptember 2012Derek Nexus
Expert Systems - The Use of Expert Systems in Drug Design-Toxicity and MetabolismJanuary 2012Derek NexusMeteor Nexus
Developing Structure-Activity Relationships for the Prediction of HepatotoxicityJune 2010Derek NexusMIP DILI
An in Silico Method for Predicting Ames Activities of Primary Aromatic AminesJanuary 2010Derek Nexus

© 2022 Lhasa Limited | Registered office: Granary Wharf House, 2 Canal Wharf, Leeds, LS11 5PS, UK Tel: +44 (0)113 394 6020
VAT number 396 8737 77 | Lhasa Limited is registered as a charity (290866)| Company Registration Number 01765239 (England and Wales).

Apart from the free survey software, we also have access to QuestionPro's free survey templates . We've found many of them useful and powerful to collect insights from various stakeholders of our organization.