Chat with us, powered by LiveChat Principal Scientist – In Silico ADME/DMPK | Lhasa Limited

Principal Scientist – In silico ADME/DMPK

Closing date: 22 February 2026

Salary & Benefits

Competitive depending on experience, plus generous benefits package, including:
34 days holiday per year (plus bank holidays) • Health care cash back • Private medical insurance • Discounted gym and retail benefits • 3 x life insurance • annual pay reviews • annual bonuses • free onsite car parking • Employee advice line • Generous pension plan

Location

Lhasa Limited, Granary Wharf House, 2 Canal Wharf, Leeds LS11 5PS. We support hybrid working with a typical week involving 2 days working from the office.

Join our team and contribute to cutting-edge research in a collaborative and innovative environment.

Shape how chemical safety decisions are made: 

As an experienced ADME or DMPK Scientist with a strong background in organic chemistry, you will play a crucial role in developing in silico solutions to support our members’ chemical safety assessmentsOur solutions help our members assess the potential toxicity of their products and ways they could be transformed by biological and chemical processes. In this full-time position, you’ll be at the forefront of developing models and methodology that underpin our solutions and collaborating with colleagues across the business to deliver these innovations to our members.

Why Lhasa Limited?

We are a successful not-for-profit company and educational charity, with an enviable reputation for collaborative scientific development. 

We develop meaningful science and software that supports the delivery of life-enhancing solutions including the development of safe chemicals to market including drugs and cosmetics as well as making a positive contribution to reducing animal testing. 

Our charitable status enables us to make altruistic decisions for the public benefit and to work with some of the leading organisations in the world to really make a difference. 

Main Responsibilities 

  • Collate and critically analyse literature and/or data relevant to the field (ADMET, DMPK, computational toxicology) 
  • Identify and interpret trends within this information to develop knowledge and decision logic that can improve chemical safety assessments 
  • Work in multifunctional teams to support the delivery of high-quality science 
  • Demonstrate initiative and problem-solving skills to contribute to the continuous improvement of our scientific methods 
  • Present scientific research across the organisation and externally through publications. 
  • Proactively maintain and improve your own professional development with support from your line manager 

Attributes

  • PhD in a relevant ADMET or DMPK discipline or similar experience 
  • Experience of working in the pharmaceutical, agrochemical, cosmetic or chemical sector 
  • Strong understanding of chemistry to be able to identify structure-activity relationships. 
  • Understanding of how chemical data is handled and can be modelled 
  • Experience of searching, retrieving and curating scientific data 
  • Excellent communication skills, with the ability to explain complex scientific concepts clearly to a range of audiences 
  • Proactive, solution focused and confident working independently as well as in a team 
  • Highly motivated, conscientious scientist with excellent attention to detail and a keen problem-solving mind 
  • Interpersonal skills and sensitivity to cultural differences to be an effective collaborator 

Our Culture

At Lhasa Limited, are committed to creating a work environment that fosters collaboration, innovation, and trust. We believe in building strong relationships within our team and with our members, working together towards our shared purpose – to enable informed decision making on chemical safety. 

Interested? Apply now

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Equal opportunities statement

Lhasa Limited aims to ensure that no job applicant, colleague, or worker receives less favourable treatment on the grounds of race, colour, caste, national or ethnic origins, sex, pregnancy or pregnancy related reasons, marital or civil partnership status, sexual orientation, disability, membership or non-membership of trade union, “spent convictions” of ex-offenders, class, age, political or religious belief.

Lhasa will make reasonable adjustments for all candidates who have declared that they have a disability at all stages in the recruitment process. Lhasa will also make reasonable adjustments, where practicable, to the workplace and methods of working to accommodate disabled applicants who require such adjustments to be made to their roles.