Lhasa Limited shared knowledge shared progress


2018 - Society of Toxicology 57th Annual Meeting and ToxExpo



The 57th SOT Annual Meeting and ToxExpo will take place from the 11-15th March 2018 in San Antonio, Texas.

Lhasa Limited will be attending the SOT and always has a full schedule of activities planned. More details of these activities can be seen below.


Exhibitor-Hosted Sessions*

Skin sensitisation: What place does in silico have within a defined approach? 

Monday 12th March

10.30 - 11.30 am

Room 217D

Testing strategies incorporating in silico predictions can provide additional value by considering factors such as metabolism, lipophilicity and chemical reactivity. Lhasa Limited will describe a defined approach integrating Derek Nexus with non-animal assays to reliably predict skin sensitisation, and will compare its performance to both human and animal data.


Ames Test Strain Profile: Implications for Mutagenicity Predictions and ICH M7

Tuesday 13th March

13.30 - 14.30 pm

Room 217D

Recent discussions around the bacterial strains used for the Ames test may impact both the development of in silico models (e.g. training sets) and the interpretation of predictions. These topics will be discussed and new features in Sarah Nexus to assist with expert review will be demonstrated.



A Defined Approach to Skin Sensitization Using Derek Nexus and Non-Animal Assays
Donna Macmillan

Tuesday, March 13, 2018
10:45am - 12:15pm

CC Exhibit Hall.

In Silico Prediction of DILI: Extraction of Histopathology Data from Preclinical Toxicity Studies of the eTOX Database for New In Silico Models of Hepatotoxicity
Alexander Amberg, Sanofi (Lilia Fisk - Co-Author)

Tuesday, March 13, 2018
10:45am - 12:15pm 

CC Exhibit Hall.

Derek Nexus and the Prediction of Human Skin Sensitization Potential: An Evaluation
Donna Macmillan
Wednesday, March 14, 2018
10:45am - 12:15pm
CC Exhibit Hall.

Addressing the Challenge of Making Negative Predictions for Skin Sensitisation
Martyn Chilton
Wednesday, March 14, 2018
1:30pm - 3:00pm 
CC Exhibit Hall.

Strain Profiles: Moving Beyond Binary Ames Classification
Adrian Fowkes 
Thursday, March 15, 2018
8:30am - 11:30am
CC Exhibit Hall.

*These sessions are Exhibitor-Hosted Sessions. Although not an official part of the SOT Annual Meeting scientific program, their presentation is permitted by the Society.


  • Headline Event (shown first above featured)

  • Featured Event

Related Publications

Back to events

© 2018 Lhasa Limited | Registered office: Granary Wharf House, 2 Canal Wharf, Leeds, LS11 5PS, UK Tel: +44 (0)113 394 6020
VAT number 396 8737 77 | Lhasa Limited is registered as a charity (290866)| Company Registration Number 01765239 (England and Wales).

Thanks to QuestionPro's generosity, we now have survey software that powers our data intelligence.