Archive
This is a library of Lhasa's blog articles.
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less than 5 minutesReplace, Reduce, Refine - How Lhasa Limited are supporting the 3Rs
Last year, a revolutionary guideline on Defined Approaches for Skin Sensitisation (OECD GL No.497) was released by the OECD. It is the first ever guideline that recommends the use of a combination of non-animal methods to predict whether a chemical can cause skin allergies. Since the publication of this guideline, Lhasa Limited have developed ‘Skin Sensitisation Defined Approach ITSv1 1.0’ – a web application containing one of the defined approaches published by the OECD, which provides hazard and potency skin sensitisation predictions without the use of animal tests. This tool is a step towards full replacement of animal testing for skin sensitisation and employs the 3Rs principle.
02 March 2022
less than 5 minutesPredicting N-nitrosamine carcinogenic potency using structure-activity relationships (SARs)
This blog article introduces an insightful publication by Lhasa Principal Scientist, Dr. David Ponting and Dr. Kevin Cross from Instem, which investigates whether improvements in structure-activity relationships can more accurately predict N-nitrosamine carcinogenic potency.
17 December 2021
less than 5 minutesHow Derek Nexus and Sarah Nexus meet the 5 OECD principles
In this article, we discuss how Derek Nexus and Sarah Nexus meet the 5 OECD principles.
30 November 2021
less than 5 minutesDerek Nexus – Achieving high accuracy with high coverage [an infographic]
In this blog piece, we explore how Derek Nexus performs when evaluated against 7 different in silico skin sensitisation models.
11 August 2021
