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  • Expert review blog
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    Is expert review an essential step when assessing mutagenic potential of drug impurities?

    A provision for the application of ‘expert knowledge’ is mentioned within the ICH M7 guideline. However, as (Q)SAR models continue to be updated and their predictive performance and structural coverage improves, this raises the question of whether expert review is still necessary… 

    05 May 2022

  • How to make mutagenicity assessment a simpler task blog image
    Clock: less than 5 minutesless than 5 minutes

    How to make mutagenicity assessment a simpler task

    A key requirement of ICH M7 is to use two complementary (Q)SAR methodologies, one expert rule-based and the second statistical-based. This blog article recognises the benefits provided when in silico systems are integrated to provide a full ICH M7 assessment in one environment.

    Discover how Lhasa Limited can help make mutagenicity assessment a simpler task, in this article!

    15 September 2021

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