This whitepaper examines how the UK Government’s Replacing Animals in Science strategy can be translated into practical implementation across regulatory and industrial contexts.
Drawing on a cross-sector discussion, it identifies key priorities for building confidence in non-animal New Approach Methodologies (NAMs), including regulatory submission confidence, Context of Use-led validation, modern benchmarking, trusted data infrastructure and international alignment.
The paper highlights where coordinated action across government, regulators, industry and scientific partners is required to support the adoption of non-animal methods in chemical safety assessment and regulatory decision-making.