Meteor 4 offers a redesigned, more intuitive platform for confident, efficient workflows, providing transparency for decision making across drug discovery and safety assessment.
With a redesigned modern interface, extended data coverage, batch processing capabilities, and enhanced interpretability, Meteor has been re-launched to help scientists evaluate metabolic fate earlier, more efficiently, and with greater clarity.
User-centric interface
Meteor 4.0 has a refreshed user interface, designed specifically to address challenges reported by ADME scientists and toxicologists, including prediction overwhelm and complex prediction setup. Our members can now generate clear results with minimal input.
Greater coverage of trusted Lhasa data
A metabolic database incorporating four years of additional data offers wider biotransformation coverage, expanding both Phase I and Phase II metabolism. The new release also includes nitrosamine biotransformation’s, reflecting recent scientific findings and regulatory expectations.
The transparent knowledge base in Meteor provides mechanistic detail, supporting references, and clear reasoning behind predicted pathways, which is essential for confident decision making in drug discovery and development.
The release brings several new and enhanced features, including:
- Batch processing: Enabling the rapid prediction of metabolic fate across compound libraries, supporting early‑stage screening workflows.
- Direct .SDF file import for batch predictions: Simplifies data handling and accelerates result generation.
- Duplicate detection & filter‑In: Allowing users to identify and compare all metabolic routes leading to the same metabolite – particularly useful in metabolite identification workflows to gain a greater understanding of metabolism coverage.
- Mass‑based filtering: Quickly and easily identify peaks in mass spectrometry results.
- New model: Built on the latest scientific knowledge, offering improved SoM (site of metabolism) confidence without relying on outdated scoring assumptions.
Integration with toxicity prediction
Meteor continues to work seamlessly with Derek Nexus and Sarah Nexus, enabling a connected, end‑to‑end in silico workflow – from metabolite prediction to toxicity and mutagenicity assessment. This integration is particularly valued by organisations needing to meet regulatory expectations for metabolite justification under ICH guidelines and make confident decisions in early safety assessment of drug candidates, saving time and money.
With increasing expectations from regulatory bodies and a growing demand for time and cost savings across pharma, generics, and chemical sectors, the new Meteor offers the user-centric features required to support both fast discovery stage exploration and confident regulatory aligned risk assessment.
For more information or to book a personalised demonstration of Meteor 4.0, speak to our team.