Excipients data sharing
Facilitating data sharing on the tolerability of pharmaceutical excipient formulations
Excipients are essential components of drug products, but they are also potential toxicants.
Understanding the levels of toxicity of pharmaceutical excipients is a crucial part of pharmaceutical drug development and often requires risk assessments to establish permissible and safe limits for these substances.
Our solution
The aim of the Lhasa Excipients data sharing initiative is to facilitate the anonymous sharing of excipient and vehicle toxicity data.
The initiative member gains access to this proprietary formulation data helping you to refine your experiments, minimize animal testing and support regulatory submissions.
Key highlights
Promotes the use of alternative methods for assessing chemicals
Participate in a data sharing consortium that actively contributes towards the reduction of animal testing. The initiative continues to aid industry data sharing and support REACH submissions by making propriety data easily accessible via a custom curated database.
Refine your experiments
Utilise proprietary data and reduce duplication of effort by quickly searching and retrieving excipient toxicity data, to help support the selection of vehicle components.
Drug substance–excipient interactions are among the hardest degradation products to anticipate. In our latest benchmarking whitepaper, Zeneth correctly predicted 59% of observed drug–excipient interaction products from real stability studies. Read the whitepaper.
Make more informed decisions
We act as the honest broker; expertly curating member donations and allowing a level of anonymity.
Through our systematic peer-review process, you can be guaranteed a high-quality dataset that you can be confident using.
Regulatory support
REACH
Among other aims, the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) aims to reduce animal testing by promoting the use of alternative methods of assessing chemicals.
The Lhasa Excipients data sharing initiative continues to aid industry data sharing and support REACH submissions by making propriety data easily accessible via a custom curated database.
Discover how you can become part of the Excipients data sharing consortium.
Related publications
Paper
- Jun 2026
- Carcinogenicity assessment, Data sharing, NAMs Strategy, UK Government Replacing Animals In Science Strategy
Paper
- Jun 2026
- Data sharing, In silico mutagenicity assessment, NAMs Strategy
Paper
- Apr 2026
- Data sharing, Nitrites
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