Lhasa Limited shared knowledge shared progress

Scientist (AOP)

Closing date: 06 September 2022


About Scientist (AOP)


From £30,000 per annum plus generous benefits package including 34 days holiday per year


Lhasa Limited, Granary Wharf House, 2 Canal Wharf, Holbeck, Leeds LS11 5PS

What is the role?

We are looking for a Scientist to join our team and develop knowledge which aids the computational assessment of the toxic potential of chemical substances.

The role will involve collecting, curating, and analysing data, to develop adverse outcome pathways (AOPs) that will be embedded in different software solutions developed at Lhasa Limited.  The role will initially focus on the development of AOPs and associated evidence (assays and in silico predictions) relating to the endpoints of Developmental and Reproductive Toxicity (DART). This work will contribute to a knowledge framework which will then be used to help reach conclusions to aid in decision making in chemical safety assessment.


Why Lhasa Limited?

We are a successful not-for-profit company and educational charity, with an enviable reputation for collaborative scientific development.



We develop meaningful science and software that supports the delivery of life-enhancing solutions including the development of safe chemicals to market including drugs and cosmetics as well as making a positive contribution to reducing animal testing.



Our charitable status enables us to make altruistic decisions for the public benefit and to work with some of the leading organisations in the world to really make a difference.



Our salaries are competitive dependent upon skills and experience.  We also We also offer fantastic personal benefits including (but not limited to); 34 days holiday plus bank holidays, a generous pension scheme, healthcare cashback, PMI and much more!

Why you?

Do you want to work somewhere where you can have an impact on day one?  Do you want to work somewhere where you can make a positive impact for yourself and others?  If so you're the type of person we are looking for!

Your responsibilities


Main Responsibilities:


  • Review existing relevant knowledge within public and private sources and convert to the AOP construct, identifying relevant molecular initiating events (MIEs), key events (KEs) and adverse outcomes (AOs)
  • Collate and critically analyse data relevant to the biological, chemical, or environmental properties of chemicals
  • Identify and interpret trends within data to develop knowledge or algorithms in organic chemistry, metabolism or toxicology that support the enhancement of Lhasa’s solutions
  • Apply new and existing methods and models that support product-relevant solutions and the progression of new software features
  • Apply reasoning between different pieces of evidence (e.g. combining predictions from different pieces of software)
  • Work in multifunctional teams to support the delivery of high quality science into the different solutions developed at Lhasa
  • Work both independently and in collaboration with others to produce effective solutions



  • Present scientific research within the science team, across the organisation and externally
  • Collaborate directly with internal partners and support collaboration with external partners
  • Represent Lhasa within professional networks




  • Proactively maintain and improve your professional development through increasing your knowledge and understanding in your field of expertise, through attending workshops, training events, conferences etc., through presenting your research, and through writing publications
  • Undertake additional tasks and responsibilities which may be reasonably expected of the role as necessary to achieve the objectives of the function and company goals

Your skills and experience


  • Domain knowledge in biology, metabolism, toxicology, organic chemistry or related disciplines
  • Experience in searching and retrieving scientific data
  • Excellent analytical and problem-solving skills and the ability to utilise new intellectual techniques where required
  • Ability to identify trends and formulate rules from complex biological or chemical data
  • Excellent written and verbal communication, presentation, and organisational skills
  • Basic domain knowledge or a keen interest in Developmental and Reproductive Toxicity and/or embryology
  • Experience of working in a scientific research or development environment and identifying new approaches/solutions to basic problems within the domain of organic chemistry, metabolism, or toxicology
  • Ability to use a range of relevant software solutions in the areas of chemistry or biology. Some knowledge of coding/scripting or using data analytics tools would be useful
  • Understanding of chemical representations and descriptors and applying mathematical or statistical methods to them
  • Ability to collate, curate and manage large volumes of chemical or biological property data or developing databases


Education and qualifications

  • Educated to degree level or equivalent in a relevant biological or chemical science
  • A PhD or Postdoctoral level or equivalent in a relevant biological or chemical science would be advantageous 


Personal characteristics

  • Conscientious with good attention to detail
  • A keen analytical mind and a desire to solve problems
  • Self-motivated and able to work independently
  • Personable and able to work in a small team
  • Excellent persuasion and influencing skills within the team




To apply send your CV, salary requirements and cover letter to recruitment@lhasalimited.org



Related documents

© 2022 Lhasa Limited | Registered office: Granary Wharf House, 2 Canal Wharf, Leeds, LS11 5PS, UK Tel: +44 (0)113 394 6020
VAT number 396 8737 77 | Lhasa Limited is registered as a charity (290866)| Company Registration Number 01765239 (England and Wales).

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