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    Lhasa Limited
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    Sep 2010
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    Poster
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Mitotic Spindle Disruption - A Mechanism for Teratogenicity.pdf

pdf fileBenz RD; Matthews EJ; Surfraz B;

Several approaches exist for the in silico prediction of teratogenicity from chemical structure [1]. A knowledge-based approach has potential for transparency, with interpretable explanations accompanying predictions. In this work we describe two of twelve chemical classes investigated which resulted in novel structural alerts suitable for in-silico prediction of teratogenicity, a potential alternative to animal testing.

Presented by Bashir Surfraz at the 38th Annual meeting of the European Teratology Society (ETS), Barcelona, Spain; 5th – 8th September 2010.

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