- Publisher:Lhasa Limited
- Publication Date:Aug 2004
- Publication Type:Poster
- Scientific Area:
- Industry Type:
METEOR. Some Recent Improvements in the Prediction of Oxidative N-Dealkylation Biotransformations
In this poster, the authors present a case study in which evaluation of twelve compounds, for which in vivo human metabolic profiles were available, led to the formulation of new rules which improved the prediction of oxidative dealkylation reactions at aromatic nitrogen centres in Meteor.
Poster presented at the 7th International ISSX Meeting, Vancouver, Canada; August 2004.