When assessing the mutagenic potential of drug impurities in silico, the ICH M7 guideline states that two complementary (Q)SAR prediction methodologies should be …
Article written by Ally Reeves with top tips provided by Sara Atkinson. A key consideration within drug substance synthesis is the potential …
The three words “replace“, “reduce” and “refine” provide an indispensable framework for performing more humane animal research. Also know as the 3Rs, …
Nitrite analysis of excipients is a new and analytically challenging area, with many organisations working quickly to determine the best practice and …
As we begin this year, I am optimistic that we are now through the worst of the COVID-19 pandemic, that has affected …
As a result of high carcinogenic potency of several N-nitrosamines in rodents, regulatory agencies are now requiring N-nitrosamine risk assessments to be …