Lhasa Limited shared knowledge shared progress

Toxicity Publications

The following links provide access to relevant Toxicity publications for the last 2 years. If you would like to view older publications, or to refine your search criteria further please search the library.

TitlePublishedTypeProducts
Derek Nexus BrochureJanuary 2018pdf fileDerek Nexus
Skin Sensitsation BrochureJanuary 2018pdf fileDerek NexusVitic Nexus
Derek Nexus Carcinogenicity QMRF.pdfDecember 2017pdf fileDerek Nexus
Derek Nexus Chromosome Damage QMRF.pdfDecember 2017pdf fileDerek Nexus
Derek Nexus Mutagenicity QMRF.pdfDecember 2017pdf fileDerek Nexus
Derek Nexus Skin Sensitisation QMRF.pdfDecember 2017pdf fileDerek Nexus
Derek Nexus HERG QMRF.pdfDecember 2017pdf fileDerek Nexus
Derek Nexus Teratogenicity QMRF.pdfDecember 2017pdf fileDerek Nexus
Drug Master File (DMF) Holders Preferred PGI Control Strategy Under ICH M7 in Support of Abbreviated New Drug Applications (ANDAs)November 2017pdf file
Profilling potential drug-induced hepatotoxicity thorugh modelling molecular initiating events (MIEs)November 2017pdf file
Understanding Negative Predictions in Derek Nexus - A Detailed WorkflowNovember 2017pdf fileDerek Nexus
Understanding Negative Predictions in Derek NexusNovember 2017pdf fileDerek Nexus
An Overview of Lhasa Limited Collaborative Data Sharing InitiativesOctober 2017pdf fileDerek NexusETOXExcipientsIntermediatesVitic Nexus
Carbamates and ICH M7 classification: Making use of expert knowledgeApril 2017Derek NexusSarah Nexus
A quantitative in silico model for predicting skin sensitization using a nearest neighbours approach within expert-derived structure–activity alert spacesMarch 2017Derek Nexus
Developmental and Reproductive Toxicity Predictions in Derek NexusMarch 2017pdf fileDerek Nexus
Computational Systems Pharmacology and Toxicology - Tools for Green Molecular Design to Reduce Toxicological RiskMarch 2017Derek NexusSarah Nexus
Redox cycling versus general liver toxicity: Read-across case study with phenolsFebruary 2017pdf file
Prediction of microvesicular liver steatosis: Read-across case study with VPA analoguesFebruary 2017pdf file
(Q)SAR tools for priority setting: A case study with printed paper and board food contact material substancesFebruary 2017Derek NexusSarah Nexus
Setaria 1.0 Installation GuideDecember 2016pdf fileSetaria
Setaria 1.0 Release NotesDecember 2016pdf fileSetaria
SEND to Vitic 1.0 ReleaseNotes.pdfNovember 2016pdf fileETOXVitic Nexus
Prediction of the effect of formulation on the toxicity of chemicalsOctober 2016
FutureTox III: Bridges for TranslationOctober 2016
Local electrophilicity as a descriptor for toxicity-relevant reactivity: A fragment-based approachSeptember 2016pdf file
Modelling the toxicity of drug-vehicle relationships: a QSAR and knowledge-base approach.July 2016pdf file
Sarah Nexus Mutagenicity QMRF.pdfMay 2016pdf fileSarah Nexus
Mechanistic Expert Call Datasets Support in silico Prediction of Teratogenicity for a Wider Chemical SpaceApril 2016Derek Nexus
Quantitative prediction of skin sensitisation potency based on structural alert spacesApril 2016Derek Nexus
Lhasa Data Sharing Experience at Bristol-Myers SquibbApril 2016pdf fileDerek Nexus
Summation of Toxicity Data in ViticMarch 2016Vitic Nexus
A tool for predicting the purging of (potentially) mutagenic impurities during synthesisMarch 2016pdf fileMirabilis
Mechanistic Expert Call Datasets Provide In Silico Prediction of Teratogenicity for a Wider Chemical SpaceMarch 2016pdf fileDerek Nexus
Quantitative prediction of skin sensitisation potency based on structural alert spacesMarch 2016pdf fileDerek Nexus
Translating from Preclinical In-Life Observations to Human Side Effects (eTOX III)March 2016pdf fileETOX
Integrating Animal Data From The Past With Future CDISC-SEND Compliant Data (eTOX Part VI)March 2016pdf fileETOX

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