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Toxicity Publications

The following links provide access to relevant Toxicity publications for the last 2 years. If you would like to view older publications, or to refine your search criteria further please search the library.

TitlePublishedTypeProducts
The eTRANSAFE Project on Translational Safety Assessment through Integrative Knowledge Management: Achievements and PerspectivesMarch 2021
Case study on the use of integrated approaches to testing and assessment for the prediction of a 90-day repeated dose toxicity study (OECD 408) for 2-Ethylbutyric acid using a read-across approach from other branched carboxylic acids.March 2021
Guidelines for FAIR sharing of preclinical safety and off-target pharmacology dataMarch 2021
2021 Webinar - An overview of Effiris 2.1; An enhanced qualitative model suite for anticipating and mitigating adverse drug reactions – Slides and recordingFebruary 2021pdf file
Utilisation of parametric methods to improve percentile-based estimates for the carcinogenic potency of nitrosaminesFebruary 2021
Beyond adverse outcome pathways: making toxicity predictions from event networks, SAR models, data and knowledgeJanuary 2021
Development of an Adverse Outcome Pathway Network to Support an Integrated Approach to Testing and Assessment of Carcinogenic RiskDecember 2020pdf file
Application of adverse outcome pathways (AOPs) to support genotoxicity assessmentNovember 2020pdf file
Introducing the concept of virtual control groups into preclinical toxicology testingSeptember 2020ETOX
Are all nitrosamines concerning? A review of mutagenicity and carcinogenicity dataSeptember 2020Derek NexusSarah NexusVitic Nexus
Pathways for N-nitroso compound formation: secondary amines and beyondJuly 2020
Do all nitrosamines pose a significant level of genotoxic risk? (Webinar Presentation Slides)July 2020pdf fileDerek NexusSarah Nexus
Derek Nexus Carcinogenicity QMRF.pdfJune 2020pdf fileDerek Nexus
Derek Nexus Chromosome Damage QMRF.pdfJune 2020pdf fileDerek Nexus
Derek Nexus Mutagenicity QMRF.pdfJune 2020pdf fileDerek Nexus
Derek Nexus Skin Sensitisation QMRF.pdfJune 2020pdf fileDerek Nexus
Derek Nexus HERG QMRF.pdfJune 2020pdf fileDerek Nexus
Sarah Nexus Mutagenicity QMRF.pdfJune 2020pdf fileSarah Nexus
Derek Nexus Teratogenicity QMRF.pdfJune 2020pdf fileDerek Nexus
The application of in silico models to support decision making in toxicologyMay 2020pdf fileDerek NexusSetariaVitic NexusZenethMirabilisSarah Nexus
Vitic Data Sharing BenefitsApril 2020pdf fileVitic Nexus
Who is using Vitic? InfographicApril 2020pdf fileVitic Nexus
Comparing and combining in silico outcomes and in vitro mechanism-based assays to predict genotoxicityMarch 2020pdf fileDerek NexusVitic Nexus
Updated Dermal Sensitisation Thresholds derived using an in silico expert system and an expanded Local Lymph Node Assay datasetMarch 2020pdf fileDerek NexusVitic Nexus
Are All Nitrosamines Concerning?March 2020pdf fileVitic Nexus
Validating proposed improvements to phototoxicity expert alerts against proprietary dataMarch 2020pdf fileDerek Nexus
Predictive Toxicology: Using In Silico SystemsOctober 2019pdf fileDerek NexusSarah Nexus
ICH M7 Expert Review Examples PresentationSeptember 2019pdf file
2019 Pharmaceutical Industry and Regulators Symposium Recording - Day 2, Part 1August 2019
2019 Pharmaceutical Industry and Regulators Symposium Recording - Day 2, Part 2August 2019
2019 Pharmaceutical Industry and Regulators Symposium Recording - Day 2, Part 4August 2019
2019 Pharmaceutical Industry and Regulators Symposium Recording - Day 1, Part 4August 2019
2019 Pharmaceutical Industry and Regulators Symposium Recording - Day 1, Part 1August 2019
2019 Pharmaceutical Industry and Regulators Symposium Recording - Day 1, Part 2August 2019
To Model or Not to Model? PosterJune 2019pdf file
In silico prediction of MutagenicityJune 2019pdf fileSarah NexusDerek Nexus
Use of In Silico Tools for Toxicity Prediction Within ICH M7June 2019pdf fileDerek NexusSarah NexusVitic Nexus
RDC53: Challenges on impurities qualificationJune 2019pdf fileDerek NexusSarah NexusVitic NexusZeneth
Use of In Silico Tools for Toxicity Prediction Within ICH M7May 2019pdf file
Modelling Simple Toxicity Endpoints: Alerts, (Q)SARs and BeyondMay 2019Derek NexusMeteor NexusSarah NexusVitic Nexus

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