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Lhasa Limited unveils new-look Carcinogenicity Database

Lhasa Limited unveils new-look Carcinogenicity Database
18 October 2016

Leeds, UK, 18/10/16 – Lhasa Limited, a not-for-profit organisation and educational charity that promotes public education through the development of computer-aided reasoning and information systems in chemistry and the related-sciences, today releases the Lhasa Carcinogenicity Database.


The Lhasa Carcinogenicity Database is founded on the Carcinogenic Potency Database (CPDB), a widely used, free resource which contains the results of long-term animal cancer tests obtained from the Carcinogenicity Potency Project. Regrettably, the original CPDB is no longer being maintained following the passing of the project director, Dr. Lois Swirsky Gold, in May 2012. Using its position as an “honest broker”, Lhasa Limited has acted to continue the public benefit that this database offers by adopting it to ensure that it remains updated and freely accessible.


In providing the Lhasa Carcinogenicity database, Lhasa Limited has built on the excellent work of all those involved in the development of the CPDB. Lhasa Limited has further curated the data by combining some duplicates that were originally considered to be distinct. Additionally, structure searching capabilities have been provided and a novel methodology for the calculation of TD50 values has been developed.


Dr. Nicholas Marchetti, Product Manager at Lhasa Limited commented – “Lhasa Limited has used its knowledge in the field of user experience to add new features, building on the excellent work of the team behind the original database. Key features include the ability to search by structure, an attractive user interface, and a novel Lhasa Limited TD50 value, which will be displayed alongside the original Gold TD50.


Lhasa Limited intends to continue maintaining the Carcinogenicity Database by searching the literature, gathering studies and compounds, and estimating the Lhasa TD50. To find out more about Lhasa Limited and the new Carcinogenicity Database, please visit our website page, contact info@lhasalimited.org or call +44 113 394 6020.



About Lhasa Limited


Lhasa Limited is an active, scientific research organisation working to promote the use of computer aided reasoning in chemistry and the life sciences. Our areas of specialisation include the development of software for toxicology and metabolism prediction, and data management. Working closely with Lhasa Limited members and the broader scientific community, Lhasa continues to draw on over 30 years of experience to create user-friendly, state-of-the-art in silico prediction and database systems.


Lhasa Limited was founded on the basis of data and knowledge sharing. Building on its reputation as the eponymous ‘honest broker’, Lhasa Limited has continued to work on the basis of ‘shared knowledge, shared progress’ for more than 30 years. Over this time, Lhasa has regularly been trusted with proprietary data and this can be seen in the many successful consortia that we continue to be involved in. The sustained success of such consortia is demonstrative of how working with Lhasa has a positive impact on the research and development process of its members.


Lhasa’s products include the Derek Nexus expert system for predicting toxicity, Sarah Nexus, a transparent statistical system for predicting mutagenicity, Vitic Nexus for managing chemical data and information, Meteor Nexus for predicting metabolic fate and Zeneth for predicting forced degradation pathways. More recently, Lhasa Limited has worked with members on the development of Mirabilis, a tool for assessing the relative purging of mutagenic impurities.





© 2021 Lhasa Limited | Registered office: Granary Wharf House, 2 Canal Wharf, Leeds, LS11 5PS, UK Tel: +44 (0)113 394 6020
VAT number 396 8737 77 | Lhasa Limited is registered as a charity (290866)| Company Registration Number 01765239 (England and Wales).

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